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Testing protease activity in the presence of a nitric oxide-generating foam

In a six-enzyme laboratory assay, the undiluted individual components and their 1:1 mixture reduced or eliminated detectable protease activity. The authors call for additional testing in wound fluid or wound-fluid surrogates.

Principal reported finding

What the publication reports

In a six-enzyme laboratory assay, the undiluted individual components and their 1:1 mixture reduced or eliminated detectable protease activity. The authors call for additional testing in wound fluid or wound-fluid surrogates.

Study context

Evidence should be read with its design.

Study type
In vitro protease assay
Publication date
Journal
Journal of Wound Care 35(Sup7a):S42–S46

Interpretation

This controlled laboratory study helps characterize protease activity in the presence of the foam. As in vitro research, it does not establish clinical efficacy in people.