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A continuous mode of action of nitric oxide in hard-to-heal wound healing

This scientific review organizes published evidence for nitric oxide across four interrelated wound-healing domains: blood flow and signaling, inflammation and immune response, microbial burden and biofilm, and tissue repair and remodeling.

Principal reported finding

What the publication reports

This scientific review organizes published evidence for nitric oxide across four interrelated wound-healing domains: blood flow and signaling, inflammation and immune response, microbial burden and biofilm, and tissue repair and remodeling.

Study context

Evidence should be read with its design.

Study type
Scientific review
Publication date
Journal
Journal of Wound Care 33(12):912–925

Interpretation

This peer-reviewed review organizes the biological rationale for nitric oxide across four wound-healing domains; it is a scientific framework, not proof of efficacy for a specific NOxy product.