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Acidified nitrite foam anti-microbial action in an ex vivo porcine dermal model

In an ex vivo porcine dermal model, one five-minute exposure prevented 4.5–8.6 log10 of biofilm growth across six pathogens. One exposure reduced mature biofilms by 1.2–2.5 log10; two exposures reduced them by 2.2–4.5 log10.

Principal reported finding

What the publication reports

In an ex vivo porcine dermal model, one five-minute exposure prevented 4.5–8.6 log10 of biofilm growth across six pathogens. One exposure reduced mature biofilms by 1.2–2.5 log10; two exposures reduced them by 2.2–4.5 log10.

Study context

Evidence should be read with its design.

Study type
Ex vivo porcine dermal model
Publication date
Journal
Journal of Wound Management 25(1):11–15

Interpretation

This tissue model helps characterize antimicrobial activity in a biologically relevant setting. It was an ex vivo porcine model, not a human clinical study.