The International Wound Journal published a peer-reviewed retrospective analysis of pressure-ulcer healing among 400 older adults in skilled nursing facilities. The study compared 200 people whose wounds were treated with nitric oxide-delivering foam with 200 propensity-matched historical standard-of-care controls.
Principal reported result
The paper reported modeled 12-week healing estimates of 63% for the nitric oxide-delivering foam group and 34% for the matched standard-of-care group. Posterior probabilities favored the foam for most stage-specific comparisons.
Study context
Propensity matching can reduce measured differences between observational groups, but it cannot eliminate unmeasured confounding. Because this study was retrospective and not randomized, the result supports an association and does not by itself establish causation. The complete paper, methods, results, and limitations are available through the DOI link below.